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DC-SIGN Mediated Sphingomyelinase-Activation and Ceramide Generation Is Essential for Enhancement of Viral Uptake in Dendritic Cells

As pattern recognition receptor on dendritic cells (DCs), DC-SIGN binds carbohydrate structures on its pathogen ligands and essentially determines host pathogen interactions because it both skews T cell responses and enhances pathogen uptake for cis infection and/or T cell trans-infection. How these...

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Hlavní autoři: Avota, Elita, Gulbins, Erich, Schneider-Schaulies, Sibylle
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040670/
https://ncbi.nlm.nih.gov/pubmed/21379338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001290
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