Differential Activation of Acid Sphingomyelinase and Ceramide Release Determines Invasiveness of Neisseria meningitidis into Brain Endothelial Cells

The interaction with brain endothelial cells is central to the pathogenicity of Neisseria meningitidis infections. Here, we show that N. meningitidis causes transient activation of acid sphingomyelinase (ASM) followed by ceramide release in brain endothelial cells. In response to N. meningitidis inf...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Simonis, Alexander, Hebling, Sabrina, Gulbins, Erich, Schneider-Schaulies, Sibylle, Schubert-Unkmeir, Alexandra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055770/
https://ncbi.nlm.nih.gov/pubmed/24945304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004160
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