Differential Activation of Acid Sphingomyelinase and Ceramide Release Determines Invasiveness of Neisseria meningitidis into Brain Endothelial Cells

The interaction with brain endothelial cells is central to the pathogenicity of Neisseria meningitidis infections. Here, we show that N. meningitidis causes transient activation of acid sphingomyelinase (ASM) followed by ceramide release in brain endothelial cells. In response to N. meningitidis inf...

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Detaylı Bibliyografya
Asıl Yazarlar: Simonis, Alexander, Hebling, Sabrina, Gulbins, Erich, Schneider-Schaulies, Sibylle, Schubert-Unkmeir, Alexandra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055770/
https://ncbi.nlm.nih.gov/pubmed/24945304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004160
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