Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide

Staphylococcus aureus (S. aureus) infections are among the most common and severe infections, garnering notoriety in an era of increasing resistance to antibiotics. It is therefore important to define molecular mechanisms by which this pathogen attacks host cells. Here, we demonstrate that alpha-tox...

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Bibliografiset tiedot
Julkaisussa:Infect Immun
Päätekijät: Becker, Katrin Anne, Fahsel, Björn, Kemper, Hannes, Mayeres, Joelina, Li, Cao, Wilker, Barbara, Keitsch, Simone, Soddemann, Matthias, Sehl, Carolin, Kohnen, Marcus, Edwards, Michael J., Grassmé, Heike, Caldwell, Charles C., Seitz, Aaron, Fraunholz, Martin, Gulbins, Erich
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736828/
https://ncbi.nlm.nih.gov/pubmed/29084896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00606-17
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