Pseudomonas aeruginosa Pyocyanin Induces Neutrophil Death via Mitochondrial Reactive Oxygen Species and Mitochondrial Acid Sphingomyelinase

Aims: Pulmonary infections with Pseudomonas aeruginosa are a serious clinical problem and are often lethal. Because many strains of P. aeruginosa are resistant to antibiotics, therapeutic options are limited. Neutrophils play an important role in the host's early acute defense against pulmonary...

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Detalles Bibliográficos
Publicado en:Antioxid Redox Signal
Main Authors: Managò, Antonella, Becker, Katrin Anne, Carpinteiro, Alexander, Wilker, Barbara, Soddemann, Matthias, Seitz, Aaron P., Edwards, Michael J., Grassmé, Heike, Szabò, Ildiko, Gulbins, Erich
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2015
Assuntos:
Forum Original Research Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403017/
https://ncbi.nlm.nih.gov/pubmed/25686490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.5979
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