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Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid

Stabilization of native three-dimensional structure has been considered for decades the main function of disulfide bonds in proteins. More recently, it was becoming increasingly clear that in addition to this static role, disulfide bonds are also important for many other aspects of protein behavior,...

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Détails bibliographiques
Publié dans:J Am Soc Mass Spectrom
Auteurs principaux: Wang, Shunhai, Kaltashov, Igor A.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401651/
https://ncbi.nlm.nih.gov/pubmed/25716754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-015-1082-5
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