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Pitfalls in protein quantitation using acid-catalyzed O(18) labeling: hydrolysis-driven deamidation

Proteolysis combined with O(18) labeling emerged recently as a powerful tool for quantitation of proteins for which suitable internal standards cannot be produced using molecular biology methods. Several recent reports suggested that acid-catalyzed O(18) labeling may be superior to the commonly acce...

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Detalhes bibliográficos
Main Authors: Wang, Shunhai, Bobst, Cedric E., Kaltashov, Igor A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173563/
https://ncbi.nlm.nih.gov/pubmed/21819098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac201657u
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