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An O(18)-labeling assisted LC-MS method for assignment of aspartyl/isoaspartyl products from Asn deamidation and Asp isomerization in proteins
An O(18)-labeling assisted LC-MS method was designed for unambiguous assignment of aspartyl/isoaspartyl products produced by Asn deamidation and Asp isomerization. By preparing the acid- and base–catalyzed deamidation standards in H(2)O(18), isomer-specific mass tags were introduced to aspartyl- and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702055/ https://ncbi.nlm.nih.gov/pubmed/23713887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac400984r |
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