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Deamidation: Differentiation of aspartyl from isoaspartyl products in peptides by electron capture dissociation

Deamidation of asparaginyl and isomerization of aspartyl residues in proteins proceed through a succinimide intermediate producing a mixture of aspartyl and isoaspartyl residues. Isoaspartic acid is an isomer of aspartic acid with the C(β) incorporated into the backbone, thus increasing the length o...

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Detalhes bibliográficos
Main Authors: Cournoyer, Jason J., Pittman, Jason L., Ivleva, Vera B., Fallows, Eric, Waskell, Lucy, Costello, Catherine E., O’Connor, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253403/
https://ncbi.nlm.nih.gov/pubmed/15659375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041062905
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