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Colistin and doripenem combinations against Pseudomonas aeruginosa: profiling the time course of synergistic killing and prevention of resistance

OBJECTIVES: Colistin is an ‘old’ drug, which is being increasingly utilized due to limited therapeutic options. However, resistance emergence during monotherapy is concerning. Here, our objective was to optimize colistin combinations against Pseudomonas aeruginosa by profiling the time course of syn...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Ly, Neang S., Bulitta, Jürgen B., Rao, Gauri G., Landersdorfer, Cornelia B., Holden, Patricia N., Forrest, Alan, Bergen, Phillip J., Nation, Roger L., Li, Jian, Tsuji, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398476/
https://ncbi.nlm.nih.gov/pubmed/25712313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku567
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