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TARGETING THE AUTOLYSIS LOOP OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR WITH CONFORMATION-SPECIFIC MONOCLONAL ANTIBODIES
Tight regulation of serine proteases is essential for their physiological functions and unbalanced states of protease activity have been implicated in a variety of human diseases. One key example is the presence of urokinase-type plasminogen activator (uPA) in different human cancer types, with high...
Shranjeno v:
| izdano v: | Biochem J |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398398/ https://ncbi.nlm.nih.gov/pubmed/21635223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110129 |
| Oznake: |
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