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TARGETING THE AUTOLYSIS LOOP OF UROKINASE-TYPE PLASMINOGEN ACTIVATOR WITH CONFORMATION-SPECIFIC MONOCLONAL ANTIBODIES

Tight regulation of serine proteases is essential for their physiological functions and unbalanced states of protease activity have been implicated in a variety of human diseases. One key example is the presence of urokinase-type plasminogen activator (uPA) in different human cancer types, with high...

詳細記述

保存先:
書誌詳細
出版年:Biochem J
主要な著者: Botkjaer, Kenneth A., Fogh, Sarah, Bekes, Erin C., Chen, Zhuo, Blouse, Grant E., Jensen, Janni M., Mortensen, Kim K., Huang, Mingdong, Deryugina, Elena, Quigley, James P., Declerck, Paul J., Andreasen, Peter A.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398398/
https://ncbi.nlm.nih.gov/pubmed/21635223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110129
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