تحميل...
Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) Inhibitors
[Image: see text] A novel series of 2-aminopyridopyrimidinone based JNK (c-jun N-terminal kinase) inhibitors were discovered and developed. Structure–activity relationships (SARs) were systematically developed utilizing biochemical and cell based assays and in vitro and in vivo drug metabolism and p...
محفوظ في:
| الحاوية / القاعدة: | ACS Med Chem Lett |
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| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Chemical
Society
2015
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| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394340/ https://ncbi.nlm.nih.gov/pubmed/25893042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500474d |
| الوسوم: |
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