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Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung
Epigenetic mechanisms involved in the establishment of lung epithelial cell lineage identities during development are largely unknown. Here, we explored the role of the histone methyltransferase Ezh2 during lung lineage determination. Loss of Ezh2 in the lung epithelium leads to defective lung forma...
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| Pubblicato in: | Development |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392602/ https://ncbi.nlm.nih.gov/pubmed/25790853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.122077 |
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