RNA-seq mixology: designing realistic control experiments to compare protocols and analysis methods

Carefully designed control experiments provide a gold standard for benchmarking different genomics research tools. A shortcoming of many gene expression control studies is that replication involves profiling the same reference RNA sample multiple times. This leads to low, pure technical noise that i...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Holik, Aliaksei Z., Law, Charity W., Liu, Ruijie, Wang, Zeya, Wang, Wenyi, Ahn, Jaeil, Asselin-Labat, Marie-Liesse, Smyth, Gordon K., Ritchie, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389713/
https://ncbi.nlm.nih.gov/pubmed/27899618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1063
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