Covering all your bases: incorporating intron signal from RNA-seq data

RNA-seq datasets can contain millions of intron reads per library that are typically removed from downstream analysis. Only reads overlapping annotated exons are considered to be informative since mature mRNA is assumed to be the major component sequenced, especially for poly(A) RNA libraries. In th...

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Publicat a:NAR Genom Bioinform
Autors principals: Lee, Stuart, Zhang, Albert Y, Su, Shian, Ng, Ashley P, Holik, Aliaksei Z, Asselin-Labat, Marie-Liesse, Ritchie, Matthew E, Law, Charity W
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Standard Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671406/
https://ncbi.nlm.nih.gov/pubmed/33575621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa073
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