Covering all your bases: incorporating intron signal from RNA-seq data

RNA-seq datasets can contain millions of intron reads per library that are typically removed from downstream analysis. Only reads overlapping annotated exons are considered to be informative since mature mRNA is assumed to be the major component sequenced, especially for poly(A) RNA libraries. In th...

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Bibliografische gegevens
Gepubliceerd in:NAR Genom Bioinform
Hoofdauteurs: Lee, Stuart, Zhang, Albert Y, Su, Shian, Ng, Ashley P, Holik, Aliaksei Z, Asselin-Labat, Marie-Liesse, Ritchie, Matthew E, Law, Charity W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671406/
https://ncbi.nlm.nih.gov/pubmed/33575621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa073
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