Covering all your bases: incorporating intron signal from RNA-seq data

RNA-seq datasets can contain millions of intron reads per library that are typically removed from downstream analysis. Only reads overlapping annotated exons are considered to be informative since mature mRNA is assumed to be the major component sequenced, especially for poly(A) RNA libraries. In th...

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Detalhes bibliográficos
Publicado no:NAR Genom Bioinform
Main Authors: Lee, Stuart, Zhang, Albert Y, Su, Shian, Ng, Ashley P, Holik, Aliaksei Z, Asselin-Labat, Marie-Liesse, Ritchie, Matthew E, Law, Charity W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Standard Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671406/
https://ncbi.nlm.nih.gov/pubmed/33575621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa073
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