Covering all your bases: incorporating intron signal from RNA-seq data

RNA-seq datasets can contain millions of intron reads per library that are typically removed from downstream analysis. Only reads overlapping annotated exons are considered to be informative since mature mRNA is assumed to be the major component sequenced, especially for poly(A) RNA libraries. In th...

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Détails bibliographiques
Publié dans:NAR Genom Bioinform
Auteurs principaux: Lee, Stuart, Zhang, Albert Y, Su, Shian, Ng, Ashley P, Holik, Aliaksei Z, Asselin-Labat, Marie-Liesse, Ritchie, Matthew E, Law, Charity W
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Standard Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671406/
https://ncbi.nlm.nih.gov/pubmed/33575621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa073
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