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Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses
Variations in sample quality are frequently encountered in small RNA-sequencing experiments, and pose a major challenge in a differential expression analysis. Removal of high variation samples reduces noise, but at a cost of reducing power, thus limiting our ability to detect biologically meaningful...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551905/ https://ncbi.nlm.nih.gov/pubmed/25925576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv412 |
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