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Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses
Variations in sample quality are frequently encountered in small RNA-sequencing experiments, and pose a major challenge in a differential expression analysis. Removal of high variation samples reduces noise, but at a cost of reducing power, thus limiting our ability to detect biologically meaningful...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551905/ https://ncbi.nlm.nih.gov/pubmed/25925576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv412 |
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