Design and Mechanism of Tetrahydrothiophene-based GABA Aminotransferase Inactivators

Low levels of γ-aminobutyric acid (GABA), one of two major neurotransmitters that regulate brain neuronal activity, are associated with many neurological disorders, such as epilepsy, Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and cocaine addiction. One of the main methods to rai...

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Detaylı Bibliyografya
Yayımlandı:J Am Chem Soc
Asıl Yazarlar: Le, Hoang V., Hawker, Dustin D., Wu, Rui, Doud, Emma, Widom, Julia, Sanishvili, Ruslan, Liu, Dali, Kelleher, Neil L., Silverman, Richard B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390550/
https://ncbi.nlm.nih.gov/pubmed/25781189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b01155
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