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Synthesis and evaluation of novel heteroaromatic substrates of GABA aminotransferase

Two principal neurotransmitters are involved in the regulation of mammalian neuronal activity, namely, γ-aminobutyric acid (GABA), an inhibitory neurotransmitter, and L-glutamic acid, an excitatory neurotransmitter. Low GABA levels in the brain have been implicated in epilepsy and several other neur...

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Detalhes bibliográficos
Main Authors: Hawker, Dustin D., Silverman, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448830/
https://ncbi.nlm.nih.gov/pubmed/22944334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.08.009
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