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Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents

To improve the potential of curcumin to treat advanced hormone-refractory prostate cancer, three series (A–C) of heteroaromatic analogs (thirty two compounds) with different monoketone linkers have been synthesized and evaluated for cytotoxicity against two human androgen-independent prostate cancer...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Samaan, Nawras, Zhong, Qiu, Fernandez, Jayjoel, Chen, Guanglin, Hussain, Ali M., Zheng, Shilong, Wang, Guangdi, Chen, Qiao-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971660/
https://ncbi.nlm.nih.gov/pubmed/24531225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2014.01.041
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