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Ornithine aminotransferase vs. GABA aminotransferase. Implications for the design of new anticancer drugs

Ornithine aminotransferase (OAT) and γ-aminobutyric acid aminotransferase (GABA-AT) are classified under the same evolutionary subgroup and share a large portion of structural, functional, and mechanistic features. Therefore, it is not surprising that many molecules that bind to GABA-AT also bind we...

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Bibliographic Details
Published in:Med Res Rev
Main Authors: Lee, Hyunbeom, Juncosa, Jose I., Silverman, Richard B.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415689/
https://ncbi.nlm.nih.gov/pubmed/25145640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21328
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