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The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM

Compartmentalized cAMP signaling regulates mitochondrial dynamics, morphology, and oxidative phosphorylation. However, regulators of the mitochondrial cAMP pathway, and its broad impact on organelle function, remain to be explored. Here, we report that Drosophila Prune is a cyclic nucleotide phospho...

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Foilsithe in:EMBO Rep
Main Authors: Zhang, Fan, Qi, Yun, Zhou, Kiet, Zhang, Guofeng, Linask, Kaari, Xu, Hong
Formáid: Artigo
Teanga:Inglês
Foilsithe: BlackWell Publishing Ltd 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388618/
https://ncbi.nlm.nih.gov/pubmed/25648146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439636
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