The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM

Compartmentalized cAMP signaling regulates mitochondrial dynamics, morphology, and oxidative phosphorylation. However, regulators of the mitochondrial cAMP pathway, and its broad impact on organelle function, remain to be explored. Here, we report that Drosophila Prune is a cyclic nucleotide phospho...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Zhang, Fan, Qi, Yun, Zhou, Kiet, Zhang, Guofeng, Linask, Kaari, Xu, Hong
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388618/
https://ncbi.nlm.nih.gov/pubmed/25648146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439636
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