[(125)I]Iodo-ASEM, a specific in vivo radioligand for α7-nAChR

[(125)I]Iodo-ASEM, a new radioligand with high affinity and selectivity for α7-nAChRs (K(i) = 0.5 nM; α7/α4β2 = 3,414), has been synthesized in radiochemical yield of 33 ± 6% from the corresponding di-butyltriazene derivative and at high specific radioactivity (1,600 Ci/mmol; 59.2 MBq/μmol). [(125)I...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucl Med Biol
Autors principals: Gao, Yongjun, Mease, Ronnie C., Olson, Thao T., Kellar, Kenneth J., Dannals, Robert F., Pomper, Martin G., Horti, Andrew G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387010/
https://ncbi.nlm.nih.gov/pubmed/25687449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.12.008
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars