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Development of [(18)F]ASEM, a specific radiotracer for quantification of the α7-nAChR with positron-emission tomography

The alpha-7 subtype of the nicotinic acetylcholine receptor (α7-nAChR) is fundamental to physiology; it mediates various brain functions and represents an important target for drug discovery. Exploration of the brain nicotinic acetylcholine receptors (nAChRs) using positron-emission tomography (PET)...

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Bibliographic Details
Published in:Biochem Pharmacol
Main Author: Horti, A.G.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600455/
https://ncbi.nlm.nih.gov/pubmed/26232729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.07.030
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