(18)F-Labeled Radiotracers for In Vivo Imaging of DREADD with Positron Emission Tomography

Designer Receptors Exclusively Activated by Designer Drugs (DREADD) are a preclinical chemogenetic approach with clinical potential for various disorders. In vivo visualization of DREADDs has been achieved with positron emission tomography (PET) using (11)C radiotracers. The objective of this study...

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Pubblicato in:Eur J Med Chem
Autori principali: Hu, Feng, Morris, Patrick J., Bonaventura, Jordi, Fan, Hong, Mathews, William B., Holt, Daniel P., Lam, Sherry, Boehm, Matthew, Dannals, Robert F., Pomper, Martin G., Michaelides, Mike, Horti, Andrew G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925357/
https://ncbi.nlm.nih.gov/pubmed/33280897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.113047
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