Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

The chemogenetic technology DREADD (designer receptors exclusively activated by designer drugs) is widely used for remote manipulation of neuronal activity in freely moving animals. DREADD technology posits the use of “designer receptors,” which are exclusively activated by the “designer drug” cloza...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Gomez, Juan L., Bonaventura, Jordi, Lesniak, Wojciech, Mathews, William B., Sysa-Shah, Polina, Rodriguez, Lionel A., Ellis, Randall J., Richie, Christopher T., Harvey, Brandon K., Dannals, Robert F., Pomper, Martin G., Bonci, Antonello, Michaelides, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309169/
https://ncbi.nlm.nih.gov/pubmed/28774929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan2475
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