Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

The chemogenetic technology DREADD (designer receptors exclusively activated by designer drugs) is widely used for remote manipulation of neuronal activity in freely moving animals. DREADD technology posits the use of “designer receptors,” which are exclusively activated by the “designer drug” cloza...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Science
Päätekijät: Gomez, Juan L., Bonaventura, Jordi, Lesniak, Wojciech, Mathews, William B., Sysa-Shah, Polina, Rodriguez, Lionel A., Ellis, Randall J., Richie, Christopher T., Harvey, Brandon K., Dannals, Robert F., Pomper, Martin G., Bonci, Antonello, Michaelides, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309169/
https://ncbi.nlm.nih.gov/pubmed/28774929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan2475
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