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DREADD: A Chemogenetic GPCR Signaling Platform

Recently, we created a family of engineered G protein-coupled receptors (GPCRs) called DREADD (designer receptors exclusively activated by designer drugs) which can precisely control three major GPCR signaling pathways (Gq, Gi, and Gs). DREADD technology has been successfully applied in a variety of...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Zhu, Hu, Roth, Bryan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368861/
https://ncbi.nlm.nih.gov/pubmed/25522378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu007
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