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DREADD: A Chemogenetic GPCR Signaling Platform
Recently, we created a family of engineered G protein-coupled receptors (GPCRs) called DREADD (designer receptors exclusively activated by designer drugs) which can precisely control three major GPCR signaling pathways (Gq, Gi, and Gs). DREADD technology has been successfully applied in a variety of...
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Publicado no: | Int J Neuropsychopharmacol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4368861/ https://ncbi.nlm.nih.gov/pubmed/25522378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu007 |
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