[(18)F]ASEM, a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor (α7-nAChR) with positron emission tomography (PET)

The α7-nicotinic cholinergic receptor (α7-nAChR) is a key mediator of brain communication and has been implicated in a wide variety of central nervous system disorders. None of the currently available PET radioligands for α7-nAChR are suitable for quantitative PET imaging, mostly due to insufficient...

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Main Authors: Horti, Andrew G., Gao, Yongjun, Kuwabara, Hiroto, Wang, Yuchuan, Abazyan, Sofya, Yasuda, Robert P., Tran, Thao, Xiao, Yingxian, Sahibzada, Niaz, Holt, Daniel P., Kellar, Kenneth J., Pletnikov, Mikhail V., Pomper, Martin G., Wong, Dean F., Dannals, Robert F.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112566/
https://ncbi.nlm.nih.gov/pubmed/24556591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.132068
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