[(18)F]ASEM, a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor (α7-nAChR) with positron emission tomography (PET)

The α7-nicotinic cholinergic receptor (α7-nAChR) is a key mediator of brain communication and has been implicated in a wide variety of central nervous system disorders. None of the currently available PET radioligands for α7-nAChR are suitable for quantitative PET imaging, mostly due to insufficient...

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Detalhes bibliográficos
Main Authors: Horti, Andrew G., Gao, Yongjun, Kuwabara, Hiroto, Wang, Yuchuan, Abazyan, Sofya, Yasuda, Robert P., Tran, Thao, Xiao, Yingxian, Sahibzada, Niaz, Holt, Daniel P., Kellar, Kenneth J., Pletnikov, Mikhail V., Pomper, Martin G., Wong, Dean F., Dannals, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112566/
https://ncbi.nlm.nih.gov/pubmed/24556591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.132068
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