[(18)F]ASEM, a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor (α7-nAChR) with positron emission tomography (PET)

The α7-nicotinic cholinergic receptor (α7-nAChR) is a key mediator of brain communication and has been implicated in a wide variety of central nervous system disorders. None of the currently available PET radioligands for α7-nAChR are suitable for quantitative PET imaging, mostly due to insufficient...

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Main Authors: Horti, Andrew G., Gao, Yongjun, Kuwabara, Hiroto, Wang, Yuchuan, Abazyan, Sofya, Yasuda, Robert P., Tran, Thao, Xiao, Yingxian, Sahibzada, Niaz, Holt, Daniel P., Kellar, Kenneth J., Pletnikov, Mikhail V., Pomper, Martin G., Wong, Dean F., Dannals, Robert F.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112566/
https://ncbi.nlm.nih.gov/pubmed/24556591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.132068
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