In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [<sup>125</sup>I]Iodo-ASEM and [<sup>18</sup>F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors

The &#945;7 nicotinic acetylcholine receptor (&#945;7 nAChR) is involved in several cognitive and physiologic processes; its expression levels and patterns change in neurologic and psychiatric diseases, such as schizophrenia and Alzheimer&#8217;s disease, which makes it a relevant drug t...

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Autors principals: Cornelius K. Donat, Henrik H. Hansen, Hanne D. Hansen, Ronnie C. Mease, Andrew G. Horti, Martin G. Pomper, Elina T. L’Estrade, Matthias M. Herth, Dan Peters, Gitte M. Knudsen, Jens D. Mikkelsen
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2020-03-01
Col·lecció:Molecules
Matèries:
alpha 7
nicotinic acetylcholine receptors
pet
nachr
autoradiography
Accés en línia:https://www.mdpi.com/1420-3049/25/6/1425
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