In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [(125)I]Iodo-ASEM and [(18)F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors

The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in several cognitive and physiologic processes; its expression levels and patterns change in neurologic and psychiatric diseases, such as schizophrenia and Alzheimer’s disease, which makes it a relevant drug target. Development of select...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Donat, Cornelius K., Hansen, Henrik H., Hansen, Hanne D., Mease, Ronnie C., Horti, Andrew G., Pomper, Martin G., L’Estrade, Elina T., Herth, Matthias M., Peters, Dan, Knudsen, Gitte M., Mikkelsen, Jens D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144377/
https://ncbi.nlm.nih.gov/pubmed/32245032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061425
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