In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [(125)I]Iodo-ASEM and [(18)F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors

The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in several cognitive and physiologic processes; its expression levels and patterns change in neurologic and psychiatric diseases, such as schizophrenia and Alzheimer’s disease, which makes it a relevant drug target. Development of select...

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Gepubliceerd in:Molecules
Hoofdauteurs: Donat, Cornelius K., Hansen, Henrik H., Hansen, Hanne D., Mease, Ronnie C., Horti, Andrew G., Pomper, Martin G., L’Estrade, Elina T., Herth, Matthias M., Peters, Dan, Knudsen, Gitte M., Mikkelsen, Jens D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144377/
https://ncbi.nlm.nih.gov/pubmed/32245032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061425
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