In Vitro and In Vivo Characterization of Dibenzothiophene Derivatives [(125)I]Iodo-ASEM and [(18)F]ASEM as Radiotracers of Homo- and Heteromeric α7 Nicotinic Acetylcholine Receptors

The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in several cognitive and physiologic processes; its expression levels and patterns change in neurologic and psychiatric diseases, such as schizophrenia and Alzheimer’s disease, which makes it a relevant drug target. Development of select...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Molecules
Prif Awduron: Donat, Cornelius K., Hansen, Henrik H., Hansen, Hanne D., Mease, Ronnie C., Horti, Andrew G., Pomper, Martin G., L’Estrade, Elina T., Herth, Matthias M., Peters, Dan, Knudsen, Gitte M., Mikkelsen, Jens D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7144377/
https://ncbi.nlm.nih.gov/pubmed/32245032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25061425
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