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Synthesis of [(125)I]IodoDPA-713, a New Probe for Imaging Inflammation

[(125)I]IodoDPA-713 [(125)I]1, which targets the translocator protein (TSPO, 18 KDa), was synthesized in seven steps from methyl-4-methoxybenzoate as a tool for quantification of inflammation in preclinical models. Preliminary in vitro autoradiography and in vivo small animal imaging were performed...

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Detalhes bibliográficos
Main Authors: Wang, Haofan, Pullambhatla, Mrudula, Guilarte, Tomas R., Mease, Ronnie C., Pomper, Martin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764231/
https://ncbi.nlm.nih.gov/pubmed/19703411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.08.102
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