TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord

We examined the phosphorylated 43-kDa TAR DNA-binding protein (pTDP-43) inclusions as well as neuronal loss in full-length spinal cords and five selected regions of the central nervous system from 36 patients with amyotrophic lateral sclerosis (ALS) and 10 age-matched normal controls. The most sever...

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Publicat a:Acta Neuropathol
Autors principals: Brettschneider, Johannes, Arai, Kimihito, Del Tredici, Kelly, Toledo, Jon B., Robinson, John L., Lee, Edward B., Kuwabara, Satoshi, Shibuya, Kazumoto, Irwin, David J., Fang, Lubin, Van Deerlin, Vivianna M., Elman, Lauren, McCluskey, Leo, Ludolph, Albert C., Lee, Virginia M.-Y., Braak, Heiko, Trojanowski, John Q.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384652/
https://ncbi.nlm.nih.gov/pubmed/24916269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1299-6
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