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Pathological TDP-43 changes in Betz cells differ from those in bulbar and spinal α-motoneurons in sporadic amyotrophic lateral sclerosis

Two nerve cells types, Betz cells in layer Vb of the primary motor neocortex and α-motoneurons of the lower brainstem and spinal cord, become involved at the beginning of the pathological cascade underlying sporadic amyotrophic lateral sclerosis (sALS). In both neuronal types, the cell nuclei forfei...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol
Autors principals: Braak, Heiko, Ludolph, Albert C., Neumann, Manuela, Ravits, John, Del Tredici, Kelly
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209403/
https://ncbi.nlm.nih.gov/pubmed/27757524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1633-2
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