Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

OBJECTIVE: To see if the distribution patterns of phosphorylated 43-kDa TAR DNA-binding protein (pTDP-43) intraneuronal inclusions in amyotrophic lateral sclerosis (ALS) permit recognition of neuropathological stages. METHODS: pTDP-43 immunohistochemistry was performed on 70 μm sections from ALS aut...

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Detalhes bibliográficos
Main Authors: Brettschneider, Johannes, Del Tredici, Kelly, Toledo, Jon B., Robinson, John L., Irwin, David J., Grossman, Murray, Suh, EunRan, Van Deerlin, Vivianna M., Wood, Elisabeth M., Baek, Young, Kwong, Linda, Lee, Edward B., Elman, Lauren, McCluskey, Leo, Fang, Lubin, Feldengut, Simone, Ludolph, Albert C., Lee, Virginia M.-Y., Braak, Heiko, Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785076/
https://ncbi.nlm.nih.gov/pubmed/23686809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23937
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