TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord

We examined the phosphorylated 43-kDa TAR DNA-binding protein (pTDP-43) inclusions as well as neuronal loss in full-length spinal cords and five selected regions of the central nervous system from 36 patients with amyotrophic lateral sclerosis (ALS) and 10 age-matched normal controls. The most sever...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Brettschneider, Johannes, Arai, Kimihito, Del Tredici, Kelly, Toledo, Jon B., Robinson, John L., Lee, Edward B., Kuwabara, Satoshi, Shibuya, Kazumoto, Irwin, David J., Fang, Lubin, Van Deerlin, Vivianna M., Elman, Lauren, McCluskey, Leo, Ludolph, Albert C., Lee, Virginia M.-Y., Braak, Heiko, Trojanowski, John Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384652/
https://ncbi.nlm.nih.gov/pubmed/24916269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1299-6
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