Microglial activation and TDP-43 pathology correlate with executive dysfunction in amyotrophic lateral sclerosis

While cognitive deficits are increasingly recognized as common symptoms in amyotrophic lateral sclerosis (ALS), the underlying histopathologic basis for this is not known, nor has the relevance of neuroinflammatory mechanisms and microglial activation to cognitive impairment (CI) in ALS been systema...

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Bibliografiske detaljer
Main Authors: Brettschneider, Johannes, Libon, David J., Toledo, Jon B., Xie, Sharon X., McCluskey, Leo, Elman, Lauren, Geser, Felix, Lee, Virginia M.-Y., Grossman, Murray, Trojanowski, John Q.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595560/
https://ncbi.nlm.nih.gov/pubmed/22210083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0932-x
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