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Amyotrophic lateral sclerosis—a model of corticofugal axonal spread

The pathological process underlying amyotrophic lateral sclerosis (ALS) is associated with the formation of cytoplasmic inclusions consisting mainly of phosphorylated 43-kDa transactive response DNA-binding protein (pTDP-43), which plays an essential part in the pathogenesis of ALS. Preliminary evid...

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Detalhes bibliográficos
Main Authors: Braak, Heiko, Brettschneider, Johannes, Ludolph, Albert C., Lee, Virginia M., Trojanowski, John Q., Del Tredici, Kelly
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943211/
https://ncbi.nlm.nih.gov/pubmed/24217521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2013.221
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