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Imaging the pathoanatomy of amyotrophic lateral sclerosis in vivo: targeting a propagation-based biological marker

OBJECTIVE: Neuropathological studies in amyotrophic lateral sclerosis (ALS) have shown a dissemination in a regional sequence in four anatomically defined patterns. The aim of this retrospective study was to see whether longitudinal diffusion tensor imaging (DTI) data support the pathological findin...

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Detalles Bibliográficos
Publicado en:J Neurol Neurosurg Psychiatry
Main Authors: Kassubek, Jan, Müller, Hans-Peter, Del Tredici, Kelly, Lulé, Dorothée, Gorges, Martin, Braak, Heiko, Ludolph, Albert C
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869447/
https://ncbi.nlm.nih.gov/pubmed/29101254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2017-316365
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