Cell intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses()

Endosomal Toll-like receptors (TLRs) play an important role in systemic autoimmune diseases such as SLE, where DNA- and RNA-associated autoantigens activate autoreactive B cells through TLR9- and TLR7-dependent pathways. Nevertheless, TLR9-deficient autoimmune prone mice develop more severe clinical...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Nündel, Kerstin, Green, Nathaniel M., Shaffer, Arthur L., Moody, Krishna-Sulayman, Busto, Patricia, Eilat, Dan, Miyake, Kensuke, Oropallo, Michael A., Cancro, Michael P., Marshak-Rothstein, Ann
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382804/
https://ncbi.nlm.nih.gov/pubmed/25681333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402425
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