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Cell intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses()
Endosomal Toll-like receptors (TLRs) play an important role in systemic autoimmune diseases such as SLE, where DNA- and RNA-associated autoantigens activate autoreactive B cells through TLR9- and TLR7-dependent pathways. Nevertheless, TLR9-deficient autoimmune prone mice develop more severe clinical...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382804/ https://ncbi.nlm.nih.gov/pubmed/25681333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402425 |
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