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Activation of Autoreactive B Cells by Endogenous TLR7 and TLR3 RNA Ligands
The key step in the activation of autoreactive B cells is the internalization of nucleic acid containing ligands and delivery of these ligands to the Toll-like Receptor (TLR) containing endolysosomal compartment. Ribonucleoproteins represent a large fraction of autoantigens in systemic autoimmune di...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501070/ https://ncbi.nlm.nih.gov/pubmed/23019335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.383000 |
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