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Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation

T cells play a significant role in the pathogenesis of systemic autoimmune diseases, including systemic lupus erythematosus; however, there is relatively little information on the nature and specificity of autoreactive T cells. Identifying such cells has been technically difficult because they are l...

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Detalles Bibliográficos
Publicado en:JCI Insight
Autores principales: Giles, Josephine R., Neves, Adriana Turqueti, Marshak-Rothstein, Ann, Shlomchik, Mark J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313065/
https://ncbi.nlm.nih.gov/pubmed/28239656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90870
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