Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation

T cells play a significant role in the pathogenesis of systemic autoimmune diseases, including systemic lupus erythematosus; however, there is relatively little information on the nature and specificity of autoreactive T cells. Identifying such cells has been technically difficult because they are l...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Giles, Josephine R., Neves, Adriana Turqueti, Marshak-Rothstein, Ann, Shlomchik, Mark J.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313065/
https://ncbi.nlm.nih.gov/pubmed/28239656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90870
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