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Autophagy Activation Protects from Mitochondrial Dysfunction in Human Chondrocytes

OBJECTIVE: Autophagy, is a key pathway of cellular homeostasis for removing damaged macromolecules and organelles, including mitochondria. Recent studies indicate that autophagy activation is defective in aging and osteoarthritis (OA), contributing to the cell death and tissue damage. In addition, t...

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書目詳細資料
發表在:Arthritis Rheumatol
Main Authors: de Figueroa, Paloma López, Lotz, Martin, Blanco, Francisco J., Caramés, Beatriz
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380780/
https://ncbi.nlm.nih.gov/pubmed/25605458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39025
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