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Autophagy Activation Protects from Mitochondrial Dysfunction in Human Chondrocytes

OBJECTIVE: Autophagy, is a key pathway of cellular homeostasis for removing damaged macromolecules and organelles, including mitochondria. Recent studies indicate that autophagy activation is defective in aging and osteoarthritis (OA), contributing to the cell death and tissue damage. In addition, t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Arthritis Rheumatol
Prif Awduron: de Figueroa, Paloma López, Lotz, Martin, Blanco, Francisco J., Caramés, Beatriz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380780/
https://ncbi.nlm.nih.gov/pubmed/25605458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39025
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