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Mitochondrial respiratory chain dysfunction modulates metalloproteases -1, -3 and -13 in human normal chondrocytes in culture

BACKGROUND: Mitochondrion has an important role in the osteoarthritis (OA) pathology. We have previously demonstrated that the alteration of the mitochondrial respiratory chain (MRC) contributes to the inflammatory response of the chondrocyte. However its implication in the process of cartilage dest...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cillero-Pastor, Berta, Rego-Pérez, Ignacio, Oreiro, Natividad, Fernandez-Lopez, Carlos, Blanco, Francisco J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750811/
https://ncbi.nlm.nih.gov/pubmed/23937653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-14-235
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